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Histological and Histomorphometric Human Results of HA-Beta-TCP 30/70 Compared to Three Different Biomaterials in Maxillary Sinus Augmentation at 6 Months: A Preliminary Report

Identifieur interne : 001100 ( Main/Exploration ); précédent : 001099; suivant : 001101

Histological and Histomorphometric Human Results of HA-Beta-TCP 30/70 Compared to Three Different Biomaterials in Maxillary Sinus Augmentation at 6 Months: A Preliminary Report

Auteurs : Susanna Annibali [Italie] ; Giovanna Iezzi [Italie] ; Gian Luca Sfasciotti [Italie] ; Maria Paola Cristalli [Italie] ; Iole Vozza [Italie] ; Carlo Mangano [Italie] ; Gerardo La Monaca [Italie] ; Antonella Polimeni [Italie]

Source :

RBID : PMC:4529888

Abstract

Objective. The aim of this investigation was to examine the bone regenerative potential of newly biphasic calcium phosphate ceramics (HA-β-TCP 30/70), by assessing histological and histomorphometric results of human specimens retrieved from sinuses augmented with HA-β-TCP 30/70, and comparing them to anorganic bovine bone (ABB), mineralized solvent-dehydrated bone allograft (MSDBA), and equine bone (EB), after a healing period of 6 months. Materials and Methods. Four consecutive patients with edentulous atrophic posterior maxilla were included in this report. A two-stage procedure was carried out for sinus augmentation with HA-β-TCP 30/70, ABB, MSDBA, and EB. After 6 months, specimens were retrieved at the time of implant placement and processed for histological and histomorphometric analyses. Results. At histological examination, all biomaterials were in close contact with the newly formed bone and showed the same pattern of bone formation; the grafted granules were surrounded by a bridge-like network of newly formed bone. A limited number of ABB particles were partially covered by connective tissue. The histomorphometric analysis revealed 30.2% newly formed bone for Ha-β-TCP 30/70, 20.1% for ABB, 16.4% for MSDBA, and 21.9% for EB. Conclusions. Within the limitations of the present investigation, these results support the successful use of HA-β-TCP 30/70 for sinus augmentation.


Url:
DOI: 10.1155/2015/156850
PubMed: 26273589
PubMed Central: 4529888


Affiliations:


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<name sortKey="La Monaca, Gerardo" sort="La Monaca, Gerardo" uniqKey="La Monaca G" first="Gerardo" last="La Monaca">Gerardo La Monaca</name>
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<p>
<italic>Objective</italic>
. The aim of this investigation was to examine the bone regenerative potential of newly biphasic calcium phosphate ceramics (HA-
<italic>β</italic>
-TCP 30/70), by assessing histological and histomorphometric results of human specimens retrieved from sinuses augmented with HA-
<italic>β</italic>
-TCP 30/70, and comparing them to anorganic bovine bone (ABB), mineralized solvent-dehydrated bone allograft (MSDBA), and equine bone (EB), after a healing period of 6 months.
<italic>Materials and Methods</italic>
. Four consecutive patients with edentulous atrophic posterior maxilla were included in this report. A two-stage procedure was carried out for sinus augmentation with HA-
<italic>β</italic>
-TCP 30/70, ABB, MSDBA, and EB. After 6 months, specimens were retrieved at the time of implant placement and processed for histological and histomorphometric analyses.
<italic>Results</italic>
. At histological examination, all biomaterials were in close contact with the newly formed bone and showed the same pattern of bone formation; the grafted granules were surrounded by a bridge-like network of newly formed bone. A limited number of ABB particles were partially covered by connective tissue. The histomorphometric analysis revealed 30.2% newly formed bone for Ha-
<italic>β</italic>
-TCP 30/70, 20.1% for ABB, 16.4% for MSDBA, and 21.9% for EB.
<italic>Conclusions</italic>
. Within the limitations of the present investigation, these results support the successful use of HA-
<italic>β</italic>
-TCP 30/70 for sinus augmentation.</p>
</div>
</front>
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<country>
<li>Italie</li>
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<li>Latium</li>
</region>
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<li>Rome</li>
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<name sortKey="Annibali, Susanna" sort="Annibali, Susanna" uniqKey="Annibali S" first="Susanna" last="Annibali">Susanna Annibali</name>
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<name sortKey="Cristalli, Maria Paola" sort="Cristalli, Maria Paola" uniqKey="Cristalli M" first="Maria Paola" last="Cristalli">Maria Paola Cristalli</name>
<name sortKey="Iezzi, Giovanna" sort="Iezzi, Giovanna" uniqKey="Iezzi G" first="Giovanna" last="Iezzi">Giovanna Iezzi</name>
<name sortKey="La Monaca, Gerardo" sort="La Monaca, Gerardo" uniqKey="La Monaca G" first="Gerardo" last="La Monaca">Gerardo La Monaca</name>
<name sortKey="Mangano, Carlo" sort="Mangano, Carlo" uniqKey="Mangano C" first="Carlo" last="Mangano">Carlo Mangano</name>
<name sortKey="Polimeni, Antonella" sort="Polimeni, Antonella" uniqKey="Polimeni A" first="Antonella" last="Polimeni">Antonella Polimeni</name>
<name sortKey="Sfasciotti, Gian Luca" sort="Sfasciotti, Gian Luca" uniqKey="Sfasciotti G" first="Gian Luca" last="Sfasciotti">Gian Luca Sfasciotti</name>
<name sortKey="Vozza, Iole" sort="Vozza, Iole" uniqKey="Vozza I" first="Iole" last="Vozza">Iole Vozza</name>
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</record>

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